• During conventional intermittent hemodialysis, urea is cleared mostly by diffusion. However, convection contributes in small amounts to urea clearance. Higher the ultrafiltration during a given treatment, more the convective clearance of urea.
  • With the use of high flux dialyzers in the current era and better middle molecule clearance, the risk of β2 microglobulin associated amyloidosis in hemodialysis patients is becoming a rarer entity.