When Kt/V drops:
- 40% of the cases occur due to decreased dialysis time or inadequate dialyzer blood flow (Qb)
- 25% of cases are due to significant access recirculation
Troubleshooting:
- Repeat measurement to confirm the drop using standardized measurement technique as described in the video “How to measure Kt/V in the HD unit”
- Confirm accuracy of post BUN measurement
- Confirm adequate Qb and time on dialysis
- Check access integrity
- Optimize Qb and Treatment time, resolve access issues
- Use a higher efficiency dialyzer (higher KoA)
- Can increase dialysate flow (Qd) although gain above 800ml/min is minimal